Ethyl chloroformate → HCID 54036922, compound

HRID 1277837Notes

Reaction equation

HRID 1277837 reaction equation
[Cl:1][C:2]([Cl:22])([Cl:21])[C:3]1[CH:4]=[C:5]([CH:18]=[CH:19][CH:20]=1)[O:6][C:7]1[CH:12]=[CH:11][C:10]([NH2:13])=[CH:9][C:8]=1[C:14]([Cl:17])([Cl:16])[Cl:15].Cl[C:24]([O:26][CH2:27][CH3:28])=[O:25]>N1C=CC=CC=1>[Cl:1][C:2]([Cl:21])([Cl:22])[C:3]1[CH:4]=[C:5]([CH:18]=[CH:19][CH:20]=1)[O:6][C:7]1[CH:12]=[CH:11][C:10]([NH:13][C:24](=[O:25])[O:26][CH2:27][CH3:28])=[CH:9][C:8]=1[C:14]([Cl:15])([Cl:16])[Cl:17]

Participants

4

Reactant 2

HCID 10928Ethyl chloroformateHCID 23451860HCID 23451860, compound

Product 1

HCID 54036922HCID 54036922, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Conditions

Temperature
5 °C

Procedure

4-[3-(Trichloromethyl)phenoxy]-3-(trichloromethyl)benzenamine (0.1 mole) and pyridine (50 ml) are charged into a glass reaction vessel fitted with a mechanical stirrer and thermometer and are cooled to about 5° C. Ethyl chloroformate (0.125 mole) is added, with stirring, at about 5° C. Stirring is continued for a period of about 30 minutes at about 5° C., then for an additional 16 hours at room temperature. The mixture is then washed with 2 portions of water (50 ml), dried and the solvent is then removed to yield the desired product ethyl [4-[3-(trichloromethyl)phenoxy]-3-(trichloromethyl)phenyl]carbamate.

Workup

  1. customfitted with a mechanical stirrer
  2. stirringStirring
  3. waitfor an additional 16 hours at room temperature
  4. washThe mixture is then washed with 2 portions of water (50 ml)
  5. customdried
  6. customthe solvent is then removed

Sources & evidence

ORD record
ord-c7f545461fef4f18a4f936316630a697
Source dataset
uspto-grants-1981_07
Patent number
US04279637

Reaction notes

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