Ethyl chloroformate → Carbamate

Participants

Reaction Conditions

Reaction Steps

4-[[3,5-Bis(ethylthio)phenyl]sulfonyl]benzenamine (0.1 mole) and pyridine (50 ml) are charged into a glass reaction vessel fitted with a mechanical stirrer and thermometer and are cooled to about 5° C. Ethyl chloroformate (0.125 mole) is added, with stirring, at about 5° C. Stirring is continued for a period of about 30 minutes at about 5° C., then for an additional 16 hours at room temperature. The mixture is then washed with 2 portions of water (50 ml), dried and the solvent is then removed to yield the desired product ethyl [4-[3,5-bis(ethylthio)phenyl]sulfonyl]phenyl]carbamate.

Provenance & Evidence