HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Methylamino)-1-benzoxepin-5(2H)-one → HCID 13446113, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Methylamino)-1-benzoxepin-5(2H)-one | HCID 13446047 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 13446113 | HCID 13446113 | — |
Reaction Steps
18.8 g (0.1 mole) 3-methylamino-1-benzoxepin-5(2H)-one is stirred with 40 g Raney Nickel in 400 ml ethanol for five hours at an hydrogen pressure of 55 bar. Subsequently, the catalyst is filtered out, the solvent is distilled off and one obtains 7.7 g (40% of the theoretical yield) racemic-2,3,4,5-tetrahydro-3-methylamino-1-benzoxepin-5-ol as an oil. The compound can be further separated as described earlier and further identified.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04279904 |
| Source dataset | uspto-grants-1981_07 |
| ORD ID | ord-b943c0d410744239aaebae8c2953c235 |
| Source note | uspto-grants-1981_07 |