反应详情

A mixture of 2.55 g of 6-(3,5-dichloro-4-methylphenyl)-3-pyridazone and 6.8 g of butyl chloroformate was heated under reflux for 1 hour. The reaction mixture was then left to cool at room temperature and the precipitate produced was collected by filtration, washed with hexane and dried under reduced pressure, giving 3.3 g (93%) of the desired Compound No. 32 in the form of colourless plates melting at 153°-157° C.

1. temperaturewas heated
2. temperatureunder reflux for 1 hour
3. waitThe reaction mixture was then left
4. customthe precipitate produced
5. filtrationwas collected by filtration
6. washwashed with hexane
7. customdried under reduced pressure