Sodium Hydroxide → HCID 23681812, compound

HRID 1277958Notes

Reaction equation

HRID 1277958 reaction equation
Br.[Cl:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]=[CH:8][C:9]3[N:10]2[CH:13]=[C:14]([C:16]([O:18]CC)=[O:17])[N:15]=3)=[CH:5][CH:4]=1.[OH-].[Na+:22]>C(O)C>[Cl:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]=[CH:8][C:9]3[N:10]2[CH:13]=[C:14]([C:16]([O-:18])=[O:17])[N:15]=3)=[CH:5][CH:4]=1.[Na+:22]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 23452494HCID 23452494, compound

Product 1

HCID 23681812HCID 23681812, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

1.37 g of ethyl 8-chloroimidazo-[1,2-a]-quinoline-2-carboxylate hydrobromide were suspended in 50 ml of ethanol and 7.7 ml of 1 N sodium hydroxide were added thereto. The mixture obtained was heated on a steam bath for 30 minutes and sodium 8-chloroimidazo-[1,2-a]-quinoline-2-carboxylate precipitated as a white solid melting at >300° C.

Workup

  1. customThe mixture obtained
  2. temperaturewas heated on a steam bath for 30 minutes
  3. customsodium 8-chloroimidazo-[1,2-a]-quinoline-2-carboxylate precipitated as a white solid melting at >300° C.

Sources & evidence

ORD record
ord-da204c6ed02642fcbc6e60bd29b78b29
Source dataset
uspto-grants-1981_07
Patent number
US04279912

Reaction notes

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