Ethyl bromopyruvate → HCID 12763968, compound

HRID 1277960Notes

Reaction equation

[NH2:1][C:2]1[CH:11]=[C:10]([O:12][CH:13]([CH3:15])[CH3:14])[C:9]2[C:4](=[CH:5][C:6]([O:16][CH3:17])=[CH:7][CH:8]=2)[N:3]=1.Br[CH2:19][C:20](=O)[C:21]([O:23][CH2:24][CH3:25])=[O:22]>>[CH3:17][O:16][C:6]1[CH:5]=[C:4]2[C:9]([C:10]([O:12][CH:13]([CH3:14])[CH3:15])=[CH:11][C:2]3[N:3]2[CH:19]=[C:20]([C:21]([O:23][CH2:24][CH3:25])=[O:22])[N:1]=3)=[CH:8][CH:7]=1

Participants

Reactant 2

HCID 66144Ethyl bromopyruvate

HCID 14067429HCID 14067429, compound

Product 1

HCID 12763968HCID 12763968, compound

Procedure

1.5 g of 2-amino-7-methoxy-4-isopropoxy-quinoline and 1.5 g of ethyl bromopyruvate were reacted by the method of Example 11 to obtain ethyl 8-methoxy-5-isopropoxyimidazo-[1,2-a]-quinoline-2-carboxylate melting at 117°-118° C.

Sources & evidence

ORD record: ord-c3739da8cd094ddba355029e79f94c19
Source dataset: uspto-grants-1981_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04279912

Reaction notes

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