反应详情

Add dropwise, with stirring, 22.5 g of 2-methoxy-1-methyl-1-pyrrolinium-methylsulfate to a solution of 6.76 g of dimethylamine in 45 ml of benzene and then boil the obtained admixture under reflux for 1 hour. Separate off the resulting heavy phase; extract it twice by shaking it out with diethyl ether and then free the extract from solvent residue in a vacuum to obtain 19.4 g (81.4% of theory) of title compound as reddish brown oil.

1. additionAdd dropwise
2. temperatureunder reflux for 1 hour
3. customSeparate off the resulting heavy phase
4. extractionextract it twice
5. stirringby shaking it out with diethyl ether
6. extractionextract from solvent residue in a vacuum