反应详情

Add dropwise, with stirring, 161 g of 1-isopropyl-2-methoxy-1-pyrrolinium-methylsulfate to a solution of 43.8 g of dimethylamine in 283 ml of benzene. Subsequently, boil the resulting reaction mixture under reflux for 1.5 hours; separate off the heavy phase and wash it 4 times with, in each case, 50 ml of diethyl ether. Dry the washed product under a high vacuum to obtain 154 g (91% of theory) of the title compound as reddish oil.

1. additionAdd dropwise
2. customthe resulting reaction mixture
3. temperatureunder reflux for 1.5 hours
4. customseparate off the heavy phase
5. washwash it 4 times with, in each case, 50 ml of diethyl ether
6. customDry the washed product under a high vacuum