HuagongsheHuagongshe Chemistry Print Report · For research reference only
Carbon Dioxide → 1-Benzyl-2-(3,4-dimethoxybenzylidene)pyrrolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Carbon Dioxide | HCID 280 | — |
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 54504210 | HCID 54504210 | — |
| Product | 1-Benzyl-2-(3,4-dimethoxybenzylidene)pyrrolidine | HCID 54271580 | — |
Reaction Steps
Boil 31.5 g of 1-benzyl-2-(α-ethoxycarbonyl-3,4-dimethoxybenzylidene)pyrrolidine under reflux with 75 ml of conc. hydrochloric acid until carbon dioxide ceases to evolve. After cooling, alkalize the thus-prepared reaction mixture with sodium hydroxide solution. Recrystallize the formed precipitate from ethanol to obtain a yield [11.3 g (44% of theory)] of title compound (m.p. 105°).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04279918 |
| Source dataset | uspto-grants-1981_07 |
| ORD ID | ord-433b592459bd485483b54aa24a7dc495 |
| Source note | uspto-grants-1981_07 |