反应详情

Boil 22.7 g of 2,2-diethoxy-1-methylpyrrolidine, 19.8 g of 4-chlorobenzylcyanide and 90 ml of benzene for 1 hour under reflux and with stirring. Distil off the volatile constituents under a vacuum. After trituration with a little diethyl ether, filter off the residue to obtain 20.8 g (68% of theory) and the title compound (m.p. 71° to 72° from isopropanol).

1. customDistil off the volatile constituents under a vacuum
2. filtrationAfter trituration with a little diethyl ether, filter off the residue
3. customto obtain 20.8 g (68% of theory)