HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzeneacetonitrile, 4-methoxy- → 2-(alpha-Cyano-4-methoxybenzylidene)-1-methylpyrrolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzeneacetonitrile, 4-methoxy- | HCID 66031 | — |
| Reactant | 2,2-Diethoxy-1-methylpyrrolidine | HCID 297308 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 2-(alpha-Cyano-4-methoxybenzylidene)-1-methylpyrrolidine | HCID 54193540 | — |
Reaction Steps
Boil 30.0 g of 2,2-diethoxy-1-methylpyrrolidine, 25 g of 4-methoxybenzylcyanide and 150 ml of benzene under reflux for 4 hours. Concentrate the refluxed reaction product and distil the residue twice under a vacuum to obtain 30.6 g (79% of theory) of the title compound (b.p. 158° at 0.005 mm of Hg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04279918 |
| Source dataset | uspto-grants-1981_07 |
| ORD ID | ord-cadd73004e0b4a8ba588c8d60535dbf8 |
| Source note | uspto-grants-1981_07 |