HCID 16039491, compound → HCID 23452562, compound

HRID 1278069Notes

Reaction equation

HRID 1278069 reaction equation
[C:1]([N:4]1[CH2:8][CH2:7][CH2:6][CH:5]1[CH2:9][C:10]1[CH:15]=[CH:14][C:13]([N+:16]([O-])=O)=[CH:12][CH:11]=1)(=[O:3])[CH3:2]>C(O)C.[Pt].[H][H]>[C:1]([N:4]1[CH2:8][CH2:7][CH2:6][CH:5]1[CH2:9][C:10]1[CH:11]=[CH:12][C:13]([NH2:16])=[CH:14][CH:15]=1)(=[O:3])[CH3:2]

Participants

4

Reactant 1

HCID 16039491HCID 16039491, compound

Product 1

HCID 23452562HCID 23452562, compound

Reagents, catalysts & solvents 2

HCID 178506450HCID 178506450, compoundCatalystHCID 702EthanolSolvent

Procedure

Hydrogenate 3.3 g of 1-acetyl-2-(4-nitrobenzyl)pyrrolidine with platinum/hydrogen in ethanol. Filter the catalyst from the hydrogenated product and concentrate the filtrate to obtain the title compound as a yellowish liquid.

Workup

  1. filtrationFilter the catalyst from the hydrogenated product
  2. concentrationconcentrate the filtrate

Sources & evidence

ORD record
ord-110d2bb030bc45b2bcfbad2a842b2370
Source dataset
uspto-grants-1981_07
Patent number
US04279918

Reaction notes

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