HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-5-bromopyridine → 1-(2-Chloro-6-fluorobenzoyl)-3-(5-bromo-2-pyridinyl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-5-bromopyridine | HCID 70622 | — |
| Reactant | 2-Chloro-6-fluorobenzoyl isocyanate | HCID 13051731 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 1-(2-Chloro-6-fluorobenzoyl)-3-(5-bromo-2-pyridinyl)urea | HCID 13023074 | — |
Reaction Steps
An 0.4 g. portion of 5-bromo-2-aminopyridine was dissolved in 20 ml. of acetonitrile, and was reacted with 0.5 g. of 2-chloro-6-fluorobenzoyl isocyanate as described in Example 1. The yield was 0.5 g. of the desired product, m.p. 207°-213° C. Elemental analysis gave the following results:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04281003 |
| Source dataset | uspto-grants-1981_07 |
| ORD ID | ord-7c714166816147db897dea6238c3c184 |
| Source note | uspto-grants-1981_07 |