HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-5-chloropyridine → Benzamide, 2-chloro-N-(((5-chloro-2-pyridinyl)amino)carbonyl)-6-fluoro-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-5-chloropyridine | HCID 66174 | — |
| Reactant | 2-Chloro-6-fluorobenzamidocarboxylic acid chloride | HCID 53797667 | — |
| Product | Benzamide, 2-chloro-N-(((5-chloro-2-pyridinyl)amino)carbonyl)-6-fluoro- | HCID 174171 | — |
Reaction Steps
A portion of 5-chloro-2-aminopyridine is reacted with 2-chloro-6-fluorobenzamidocarboxylic acid chloride in the presence of a hydrogen halide acceptor as described in Example 12. The product, named in the heading above, is isolated as described in Example 12 to obtain the desired compound, identical to the product of Example 3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04281003 |
| Source dataset | uspto-grants-1981_07 |
| ORD ID | ord-0cf6ec76afe74b3dbc3b15707b9e3905 |
| Source note | uspto-grants-1981_07 |