Potassium Hydroxide → HCID 70577748, compound

HRID 1278191Notes

Reaction equation

C[O:2][C:3]([C:5]1[CH:10]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([N+:17]([O-:19])=[O:18])[CH:12]=2)[C:9]([C:20]([O:22][CH:23]([CH3:25])[CH3:24])=[O:21])=[C:8]([CH3:26])[NH:7][N:6]=1)=[O:4].[OH-].[K+]>>[CH:23]([O:22][C:20]([C:9]1[CH:10]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([N+:17]([O-:19])=[O:18])[CH:12]=2)[C:5]([C:3]([OH:4])=[O:2])=[N:6][NH:7][C:8]=1[CH3:26])=[O:21])([CH3:25])[CH3:24]

Participants

Reactant 2

HCID 14797Potassium Hydroxide

HCID 70576179HCID 70576179, compound

Product 1

HCID 70577748HCID 70577748, compound

Procedure

0.1 mol of 1,4-dihydro-6-methyl-4-(3-nitrophenyl)-pyridazine-3,5-dicarboxylic acid 5-isopropyl 3-methyl ester is saponified with 0.105 mol of KOH analogously to Example 28 to give 1,4-dihydro-6-methyl-4-(3-nitrophenyl)-pyridazine-3,5-dicarboxylic acid 5-isopropyl ester. Melting point 195° C. (ethanol)

Sources & evidence

ORD record: ord-63251780d72447eb96f6b91a3427bf77
Source dataset: uspto-grants-1981_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04280998

Reaction notes

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