Potassium Hydroxide → HCID 21162980, compound

HRID 1278193Notes

Reaction equation

C([O:3][C:4]([C:6]1[CH:11]([C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([N+:18]([O-:20])=[O:19])[CH:13]=2)[C:10]([C:21]([O:23]CC)=[O:22])=[C:9]([CH3:26])[NH:8][N:7]=1)=[O:5])C.[OH-].[K+]>>[CH3:26][C:9]1[NH:8][N:7]=[C:6]([C:4]([OH:5])=[O:3])[CH:11]([C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([N+:18]([O-:20])=[O:19])[CH:13]=2)[C:10]=1[C:21]([OH:23])=[O:22]

Participants

Reactant 2

HCID 14797Potassium Hydroxide

HCID 70576892HCID 70576892, compound

Product 1

HCID 21162980HCID 21162980, compoundYield 71%

Procedure

0.1 mol of 1,4-dihydro-6-methyl-4-(3-nitrophenyl)-pyridazine-3,5-dicarboxylic acid diethyl ester is saponified with 0.25 mol of KOH analogously to Example 28 to give 1,4-dihydro-6-methyl-4-(3-nitrophenyl)-pyridazine-3,5-dicarboxylic acid. Melting point 169° C. (decomposition).

Sources & evidence

ORD record: ord-b55c1e1b7ab14dff8f7e5a6a321600e1
Source dataset: uspto-grants-1981_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04280998

Reaction notes

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