1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one → 7-(3-Pyridyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile

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Reaction Steps

A mixture of 17.61 g. of 3-dimethylamino-1-(3-pyridyl)-2-propen-1-one and 10.8 g. of 3-aminopyrazole-4-carbonitrile in 75 ml. of glacial acetic acid is heated at reflux temperature for 6 hours. The procedure described in Example 1 is continued to give the product of the example as tan crystals, m.p. 258°-260° C.

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