1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one → HCID 11299190, compound

HRID 1278196Notes

Reaction equation

HRID 1278196 reaction equation
[NH2:1][C:2]1[C:6]([Cl:7])=[CH:5][NH:4][N:3]=1.CN(C)[CH:10]=[CH:11][C:12]([C:14]1[CH:15]=[N:16][CH:17]=[CH:18][CH:19]=1)=O>C(O)(=O)C>[Cl:7][C:6]1[CH:5]=[N:4][N:3]2[C:12]([C:14]3[CH:15]=[N:16][CH:17]=[CH:18][CH:19]=3)=[CH:11][CH:10]=[N:1][C:2]=12

Participants

4

Reactant 2

HCID 5670331-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-oneHCID 178509265HCID 178509265, compound

Product 1

HCID 11299190HCID 11299190, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

As for Example 2, 3-amino-4-chloropyrazole is heated at reflux temperature for 6 hours with 3-dimethylamino-1-(3-pyridyl)-2-propen-1-one in glacial acetic acid to give the product of the example, m.p. 225°-226° C.

Workup

  1. customto give the product of the example, m.p. 225°-226° C.

Sources & evidence

ORD record
ord-62415bafd9c34827954af10cf6c049fb
Source dataset
uspto-grants-1981_07
Patent number
US04281000

Reaction notes

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