Pyrazole, 3-amino-4-cyano-5-ethyl- → 2-Ethyl-7-(3-pyridyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile

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Reaction Steps

As for Example 2, 2.72 g. of 3-amino-5-ethylpyrazole-4-carbonitrile is heated at reflux temperature for 16 hours with 3.52 g. of 3-dimethylamino-1-(3-pyridyl)-2-propen-1-one in 25 ml. of glacial acetic acid to give 2.65 g. of the product of the example as colorless crystals, m.p. 170°-172° C.

Provenance & Evidence