1-Chlorobenzotriazole → 3-Chloro-2-ethyl-7-(3-pyridyl)pyrazolo[1,5-a]pyrimidine

HRID 1278233Notes

Reaction equation

HRID 1278233 reaction equation
[CH2:1]([C:3]1[CH:17]=[C:6]2[N:7]=[CH:8][CH:9]=[C:10]([C:11]3[CH:12]=[N:13][CH:14]=[CH:15][CH:16]=3)[N:5]2[N:4]=1)[CH3:2].[Cl:18]N1C2C=CC=CC=2N=N1>ClCCl>[Cl:18][C:17]1[C:3]([CH2:1][CH3:2])=[N:4][N:5]2[C:10]([C:11]3[CH:12]=[N:13][CH:14]=[CH:15][CH:16]=3)=[CH:9][CH:8]=[N:7][C:6]=12

Participants

4

Reactant 2

HCID 887611-ChlorobenzotriazoleHCID 127662552-Ethyl-7-(3-pyridyl)pyrazolo[1,5-a]pyrimidine

Product 1

HCID 127662563-Chloro-2-ethyl-7-(3-pyridyl)pyrazolo[1,5-a]pyrimidine

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

As for Example 34, 1.95 g. of 2-ethyl-7-(3-pyridyl)pyrazolo[1,5-a]pyrimidine is reacted with 1.47 g. of N-chlorobenzotriazole in 50 ml. of dichloromethane to give the product of the example, m.p. 132°-133° C.

Sources & evidence

ORD record
ord-057d6c928c00422d9754463cd067fe2b
Source dataset
uspto-grants-1981_07
Patent number
US04281000

Reaction notes

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