HCID 54357126, compound → HCID 21163067, compound

HRID 1278240Notes

Reaction equation

HRID 1278240 reaction equation
C[N:2]([CH3:14])[CH:3]=[CH:4][C:5]([C:7]1[CH:12]=[CH:11][C:10]([CH3:13])=[CH:9][N:8]=1)=O.N[C:16]1[C:20]([C:21]([O:23][CH2:24][CH3:25])=[O:22])=C[NH:18][N:17]=1>C(O)(=O)C>[CH3:13][C:10]1[CH:11]=[CH:12][C:7]([C:5]2[N:18]3[N:17]=[CH:16][C:20]([C:21]([O:23][CH2:24][CH3:25])=[O:22])=[C:14]3[N:2]=[CH:3][CH:4]=2)=[N:8][CH:9]=1

Participants

4

Reactant 2

HCID 54357126HCID 54357126, compoundHCID 178469928HCID 178469928, compound

Product 1

HCID 21163067HCID 21163067, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A mixture of 0.01 mole of 3-dimethylamino-1-(5-methyl-2-pyridyl)-2-propen-1-one and 0.01 mole of ethyl 3-aminopyrazole-4-carboxylate in glacial acetic acid is refluxed for 6 hours. The solvent is removed under reduced pressure and the residue worked up as for Example 53 to give the product of the example.

Workup

  1. temperatureis refluxed for 6 hours
  2. customThe solvent is removed under reduced pressure
  3. customto give the product of the example

Sources & evidence

ORD record
ord-d5359313457d4f2288603f170366a6c6
Source dataset
uspto-grants-1981_07
Patent number
US04281000

Reaction notes

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