HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Acetylpyridine → 3-Dimethylamino-1-(2-pyridyl)prop-2-en-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Acetylpyridine | HCID 14286 | — |
| Reactant | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Product | 3-Dimethylamino-1-(2-pyridyl)prop-2-en-1-one | HCID 566993 | — |
Reaction Steps
A mixture of 25 g. of 2-acetylpyridine and 35 ml. of N,N-dimethylformamide dimethylacetal is refluxed for 16 hours. The mixture is cooled and filtered to give 3-dimethylamino-1-(2-pyridyl)-2-propen-1-one as crystals, m.p. 127°-130° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04281000 |
| Source dataset | uspto-grants-1981_07 |
| ORD ID | ord-fba50ffebeec490ab54d32fcab05d345 |
| Source note | uspto-grants-1981_07 |