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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1278250Generated: November 3, 2026

7-Phenylacetamido-8-oxo-2,2-dimethyl-3-oxa-1-azabicyclo[4.2.0]octane → 1-(2-Tetrahydropyranyl)-3-phenylacetamido-4-[2-(2-tetrahydropyranyl)oxyethyl]-2-azetidinone

https://huagongshe.com/reaction/1278250

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-Phenylacetamido-8-oxo-2,2-dimethyl-3-oxa-1-azabicyclo[4.2.0]octaneHCID 12804735—
Reactant1-(2-Tetrahydropyranyl)-3-amino-4-[2-(2-tetrahydropyranyl)oxyethyl]-2-azetidinoneHCID 21163112—
Product1-(2-Tetrahydropyranyl)-3-phenylacetamido-4-[2-(2-tetrahydropyranyl)oxyethyl]-2-azetidinoneHCID 54145837—

Reaction Steps

Following the procedure described for the preparation of 7-phenylacetamido-8-oxo-2,2-dimethyl-3-oxa-1-azabicyclo[4.2.0]octane from 7-amino-8-oxo-2,2-dimethyl-3-oxa-1-azabicyclo[4.2.0]octane (Example 6) and using 1-(2-tetrahydropyranyl)-3-amino-4-[2-(2-tetrahydropyranyl)oxyethyl]-2-azetidinone there is obtained 1-(2-tetrahydropyranyl)-3-phenylacetamido-4-[2-(2-tetrahydropyranyl)oxyethyl]-2-azetidinone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04281002
Source datasetuspto-grants-1981_07
ORD IDord-aad95eea234540eb90ad37ebcc8ea6b6
Source noteuspto-grants-1981_07