Quinoline → HCID 53787794, compound

HRID 1278274Notes

Reaction equation

HRID 1278274 reaction equation
[O:1]([CH2:8][CH2:9][CH2:10][O:11][C:12]1[CH:27]=[CH:26][C:15]2[C:16](=[O:25])[CH:17]=[C:18]([C:20]#[C:21][C:22]([OH:24])=[O:23])[O:19][C:14]=2[CH:13]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.N1C2C(=CC=CC=2)C=CC=1>C(O)C.[Pd]>[O:1]([CH2:8][CH2:9][CH2:10][O:11][C:12]1[CH:27]=[CH:26][C:15]2[C:16](=[O:25])[CH:17]=[C:18]([CH:20]=[CH:21][C:22]([OH:24])=[O:23])[O:19][C:14]=2[CH:13]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

5

Reactant 2

HCID 7047QuinolineHCID 21163154HCID 21163154, compound

Product 1

HCID 53787794HCID 53787794, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

3-[7-(3-Phenoxypropyloxy)-4-oxo-4H-1-benzopyran-2-yl]propiolic acid (1 g) in ethanol was hydrogenated at atmospheric pressure in the presence of palladium on barium sulphate poisoned with quinoline. Isolation procedures yielded the title acrylic acid.

Sources & evidence

ORD record
ord-44884e225d1244ed87f328302a105ae2
Source dataset
uspto-grants-1981_07
Patent number
US04281008

Reaction notes

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