Sodium Hydroxide → Sodium 4-(allylamino)phenylacetate

HRID 1278301Notes

Reaction equation

HRID 1278301 reaction equation
[CH2:1]([NH:4][C:5]1[CH:10]=[CH:9][C:8]([CH2:11][C:12]([OH:14])=[O:13])=[CH:7][CH:6]=1)[CH:2]=[CH2:3].[OH-].[Na+:16]>O.C(O)C>[CH2:1]([NH:4][C:5]1[CH:10]=[CH:9][C:8]([CH2:11][C:12]([O-:14])=[O:13])=[CH:7][CH:6]=1)[CH:2]=[CH2:3].[Na+:16]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 38316Acetic acid, 2-(p-(allylamino)phenyl)-

Product 1

HCID 23720721Sodium 4-(allylamino)phenylacetate

Reagents, catalysts & solvents 1

HCID 19096565Water ethanolSolvent

Procedure

A mixture of 3.62 g. of 4-(allylamino)phenylacetic acid and 25 ml. of ethanol water (9:1) containing 0.400 g. of sodium hydroxide is stirred for 4 hours. The mixture is filtered and the residue washed with 10 ml. of ethanol-water (9:1) and dried in vacuo for 24 hours to yield sodium 4-(allylamino)phenylacetate as a white solid.

Workup

  1. additionA mixture of 3.62 g
  2. filtrationThe mixture is filtered
  3. washthe residue washed with 10 ml
  4. dry with materialof ethanol-water (9:1) and dried in vacuo for 24 hours

Sources & evidence

ORD record
ord-9f6926eaab14403a8e5c014dd4ff83e9
Source dataset
uspto-grants-1981_07
Patent number
US04281019

Reaction notes

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