HuagongsheHuagongshe Chemistry Print Report · For research reference only
Boron trifluoride etherate → 2-Ethoxyethyl 4-(allylamino)phenylacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Boron trifluoride etherate | HCID 8000 | — |
| Reactant | Glycol monoethyl ether | HCID 8076 | — |
| Reactant | Acetic acid, 2-(p-(allylamino)phenyl)- | HCID 38316 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 2-Ethoxyethyl 4-(allylamino)phenylacetate | HCID 21163497 | — |
Reaction Steps
A solution of 11.8 g. of 4-(allylamino)phenylacetic acid, 1.00 g. of 2-ethoxyethanol and 5.35 ml. of boron trifluoride etherate in 200 ml. toluene is stirred under reflux for 48 hours. The solution is treated with an additional 5.35 ml. of boron trifluoride etherate and refluxing is continued for 120 hours. Dilution with water and methylene chloride followed by filtration affords 2-ethoxyethyl 4-(allylamino)phenylacetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04281019 |
| Source dataset | uspto-grants-1981_07 |
| ORD ID | ord-d66ae47ab2a84e54a67f157623781452 |
| Source note | uspto-grants-1981_07 |