HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lactic Acid → 1-Carboxyethyl 4-(allylamino)phenylacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lactic Acid | HCID 612 | — |
| Reactant | 2-Methylbenzenesulfonic acid | HCID 6925 | — |
| Reactant | Acetic acid, 2-(p-(allylamino)phenyl)- | HCID 38316 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 1-Carboxyethyl 4-(allylamino)phenylacetate | HCID 21163479 | — |
Reaction Steps
A flask containing 10.0 g. 4-(allylamino)phenylacetic acid, 3.3 g. lactic acid, 500 mg. toluenesulfonic acid and 500 ml. toluene equipped with a Soxhlet extractor charged with activated 4 A Linde molecular sieves. The solution is refluxed for 24 hours during which time the Soxhlet extractor is charged twice more with fresh sieves. The hot solution is filtered and left to cool, whereupon 1-carboxyethyl 4-(allylamino)phenylacetate separates as off-white crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04281019 |
| Source dataset | uspto-grants-1981_07 |
| ORD ID | ord-6622ab184a5541cfa3a43ead1ecfb10d |
| Source note | uspto-grants-1981_07 |