Ethylamine → HCID 53733537, compound

HRID 1278332Notes

Reaction equation

HRID 1278332 reaction equation
[CH2:1]([NH2:3])[CH3:2].C([O:6][C:7]([C:9]1[S:10][C:11]([S:14][CH2:15][CH3:16])=[N:12][N:13]=1)=O)C>>[CH2:1]([NH:3][C:7]([C:9]1[S:10][C:11]([S:14][CH2:15][CH3:16])=[N:12][N:13]=1)=[O:6])[CH3:2]

Participants

3

Reactant 2

HCID 6341EthylamineHCID 54153621HCID 54153621, compound

Product 1

HCID 53733537HCID 53733537, compound

Conditions

Temperature
4 °C

Procedure

54 g of an aqueous 50% ethylamine solution were added to 43.7 g of the compound obtained in Example 8(c), that is ethylthio-1,3,4-thiadiazole-2-carboxylic acid ethyester. This caused the temperature to rise to 46° C. The solution was subsequently heated to boiling point for another 15 minutes. It was then cooled to 4° C. and reacted with 50 ml icewater. The precipitated compound was removed by suction.

Workup

  1. customto rise to 46° C
  2. temperatureThe solution was subsequently heated
  3. customfor another 15 minutes
  4. customreacted with 50 ml icewater
  5. customThe precipitated compound was removed by suction

Sources & evidence

ORD record
ord-6a1c4c6f2b114ee08cfc224d14aa83cb
Source dataset
uspto-grants-1981_07
Patent number
US04281121

Reaction notes

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