Ammonia → HCID 13566351, compound

HRID 1278333Notes

Reaction equation

HRID 1278333 reaction equation
C([O:3][C:4]([C:6]1[S:7][C:8]([S:11][CH3:12])=[N:9][N:10]=1)=O)C.[NH3:13]>C(O)C>[CH3:12][S:11][C:8]1[S:7][C:6]([C:4]([NH2:13])=[O:3])=[N:10][N:9]=1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 20786208HCID 20786208, compound2×

Product 1

HCID 13566351HCID 13566351, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

11.8 g of 5-methylthio-1,3,4-thiadiazole-2-carboxylic acid ethylester which is the compound obtained in Example 10, were mixed with 50 ml ethanol and 50 ml of a 25% aqueous ammonia solution whereupon the mixture was heated for 15 minutes on a steam bath. After cooling part of the reaction product precipitated. The precipitation was completed by adding ice water. The precipitate was then removed by suction and dried in a vacuum.

Workup

  1. temperaturewas heated for 15 minutes on a steam bath
  2. temperatureAfter cooling part of the reaction product
  3. customprecipitated
  4. customThe precipitation
  5. additionby adding ice water
  6. customThe precipitate was then removed by suction
  7. customdried in a vacuum

Sources & evidence

ORD record
ord-ead33e19b45d44aab1c725eb022fe152
Source dataset
uspto-grants-1981_07
Patent number
US04281121

Reaction notes

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