HuagongsheHuagongshe Chemistry Print Report · For research reference only
Malononitrile → 4-Chloro-3-dicyanomethylene-5-ethoxycarbonyl-2-methyl-4-isothiazoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Malononitrile | HCID 8010 | — |
| Reactant | 3,4-Dichloro-2-methyl-5-ethoxycarbonylisothiazolium fluorosulfonate | HCID 12889013 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | 4-Chloro-3-dicyanomethylene-5-ethoxycarbonyl-2-methyl-4-isothiazoline | HCID 12889045 | 44% |
Reaction Steps
3,4-Dichloro-5-ethoxycarbonyl-2-methylisothiazolium fluorosulfonate (7.5 g, 0.022 mole) was dissolved in 75 ml of isopropanol. Malononitrile (1.5 g, 0.023 mol) was added the mixture stirred for 30 min. The yellow solid was collected and washed with isopropanol to yield 2.6 g (44%) of product, mp 134-136. Analysis calculated for C10H8ClN3O2S2 : C 44.51; H, 3.00; Cl, 13.16; N, 15.57; S, 11.90. Found: C, 44.34; H, 2.82; Cl, 12.60; N, 14.82; S, 11.42.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04281136 |
| Source dataset | uspto-grants-1981_07 |
| ORD ID | ord-2302ec7c8212461cbe166c33c0ac7826 |
| Source note | uspto-grants-1981_07 |