HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-Dichloro-2-methyl-5-ethoxycarbonylisothiazolium fluorosulfonate → 4-Chloro-5-ethoxycarbonyl-2-methyl-4-isothiazolin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-Dichloro-2-methyl-5-ethoxycarbonylisothiazolium fluorosulfonate | HCID 12889013 | — |
| Solvent | Potassium Carbonate | HCID 11430 | — |
| Product | 4-Chloro-5-ethoxycarbonyl-2-methyl-4-isothiazolin-3-one | HCID 12889059 | 37.6% |
Reaction Steps
3,4-Dichloro-5-ethoxycarbonyl-2-methylisothiazolium fluorosulfonate (4.2 g, 0.012 mol) was added to 50 ml of saturated K2CO3 solution. The aqueous phase was extracted with 3×50 ml of CH2Cl2. Then combined extracts were dried (MgSO4), filtered and conc. to yield a solid. Recrystallization from heptane yielded 1.0 g (35%) of 4-chloro-5-ethoxycarbonyl-2-methyl-4-isothiazolin-3-one, mp 142-147.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04281136 |
| Source dataset | uspto-grants-1981_07 |
| ORD ID | ord-21f276798cbe472f9feee595215a9664 |
| Source note | uspto-grants-1981_07 |