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Sodium Cyanide → 12-Hydroxydodecanenitrile
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium Cyanide | HCID 8929 | — |
| 反応物 | 11-Bromo-1-undecanol | HCID 74163 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 12-Hydroxydodecanenitrile | HCID 10330348 | — |
反応手順
A solution 4.6 g. of 11-bromoundecanol and 1.6 g. of sodium cyanide in 40 ml. of dimethylformamide is heated at 80° C. for 18 hours, cooled, and poured into ice-water. The mixture is extracted with methylene chloride and the extract is dried over anhydrous magnesium sulfate. Evaporation of the solution affords 12-hydroxydodecanonitrile as a yellow oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04281018 |
| 出典データセット | uspto-grants-1981_07 |
| ORD ID | ord-1d9be8fa42bd4aa28b64c51da6d1f1bc |
| 出典メモ | uspto-grants-1981_07 |