HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Ethyl 4-(15-carboxypentadecylamino)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Ethyl 4-(15-carbomethoxypentadecylamino)benzoate | HCID 21163354 | — |
| Solvent | Water | HCID 962 | — |
| Product | Ethyl 4-(15-carboxypentadecylamino)benzoate | HCID 21163318 | — |
Reaction Steps
A solution of 5 g. of ethyl 4-(15-carbomethoxypentadecylamino)benzoate and 0.8 g. of potassium hydroxide in 50 ml. of 95% ethanol is stirred at 50° C. for 10 hours, diluted with 100 ml. of water and acidified with concentrated hydrochloric acid. The solid is collected by filtration, dried, and recrystallized from toluene to yield ethyl 4-(15-carboxypentadecylamino)benzoate as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04281018 |
| Source dataset | uspto-grants-1981_07 |
| ORD ID | ord-07feee91c2e54311bfdfccd264d79366 |
| Source note | uspto-grants-1981_07 |