Acrylamide → HCID 23451639, compound

Participants

Reaction Steps

A mixture of 71.1 g (1.0 mole) acrylamide, 0.5 g triethylamine, 0.5 g 2,6-ditert-butyl-4-methylphenol and 250 ml benzene is mixed with 110.8 g (1.05 mole) 2-chloroethyl isocyanate and heated in an autoclave over a period of 10 hours to 110° C. The finely crystalline precipitate obtained on cooling is filtered off. 140 g of substance is so obtained. It is recrystallized from 700 ml acetonitrile to yield 115 g (0.65 mole=65% of theory) white crystal needles having a melting point between 156° and 158° C.

Provenance & Evidence