2,6-Dimethylphenol → HCID 23451691, compound

Participants

Reaction Conditions

Reaction Steps

2,6-Dimethylphenol (2.4 g, 0.02 mol) was added to a solution of Ba(OH)2.8H2O (6.6 g, 0.021 mol) in distilled water (12 mL). The mixture was cooled to 15° C. and 2-isopropylidene-1,4-dichlorobutane (3.6 g, 0.022 mol) was added over 1 hour under nitrogen. Stirring at room temperature was continued for 5 hours and then the reaction mixture was extracted with ether. The ether extracts were washed with 10% sodium hydroxide, water, and dried (Na2SO4). Concentration gave 4.7 g of crude material which was mainly the alkylated phenol having the structure: ##STR33## A sample purified by preparative glc had the following spectral characteristics:

Provenance & Evidence