HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 3-oxo-5-(1,3-thiazole-2-yl)-4-pentenoate → HCID 12112919, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 3-oxo-5-(1,3-thiazole-2-yl)-4-pentenoate | HCID 69948902 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 12112919 | HCID 12112919 | 97.6% |
Reaction Steps
A mixture of methyl 3-oxo-5-(1,3-thiazole-2-yl)-4-pentenoate (132.0 g) and palladium hydroxide, 20 wt % on carbon (13 g) in MeOH (2600 ml) was stirred under hydrogen atmosphere by balloon for 4 hours. Catalyst was removed by filtration and the filtrate evaporated to give 130.0 g of methyl 3-oxo-5-(1,3-thiazole-2-yl)pentanoate as a brown liquid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06444677B2 |
| Source dataset | uspto-grants-2002_09 |
| ORD ID | ord-67dc16ec11a34ac88b0001f464a17378 |
| Source note | uspto-grants-2002_09 |