Acrylonitrile → HCID 21935997, compound

Participants

Reaction Steps

A mixture of acrylonitrile (5.6 ml/85.1 mmol) and benzylpiperazine (5.0 g/28.3 mmol) in benzene (28 ml) was refluxed for 10 hours. After cooling down, the mixture was concentrated in vacuo and the residue was purified by column chromatography (NH2 gel/200-350 mesh/100 g/dichloromethane) to give a pale brown oil (5.5 g/85%).

Provenance & Evidence