HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanolamine → 4-Fluoro-N-(2-hydroxyethyl)benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanolamine | HCID 700 | — |
| Reactant | 4-Fluorobenzenesulfonyl chloride | HCID 9588 | — |
| Product | 4-Fluoro-N-(2-hydroxyethyl)benzenesulfonamide | HCID 1587683 | — |
Reaction Steps
The title compound was prepared according to the procedure of Intermediate 33 from 3.97 g (20 mmol) of 4-fluorobenzenesulfonyl chloride and 3.11 g (50 mmol) of ethanolamine, yielding 3.0 g of a white solid; m.p. 77-78° C.; MS (ES) m/z 219.8 (MH+); HRMS (EI) Calcd. for C8H10FNO3S (M+): 219.0366, Found: 219.0369.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06444685B1 |
| Source dataset | uspto-grants-2002_09 |
| ORD ID | ord-ac12dfeaa76f4340b608541a144041c5 |
| Source note | uspto-grants-2002_09 |