Methanimidamide, N,N-diphenyl- → 3-Anilinoprop-2-enenitrile

HRID 1278861ノート

反応式

HRID 1278861 の反応式
[N:1]1(CCOC2C=C(CC#N)C=CC=2)CCOCC1.[C:19]1([N:25]([C:28]2[CH:33]=[CH:32]C=CC=2)C=N)[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>C1(C)C(C)=CC=CC=1.CCCCCC>[C:19]1([NH:25][CH:28]=[CH:33][C:32]#[N:1])[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=1

参加物

5

反応物 2

HCID 78296Methanimidamide, N,N-diphenyl-HCID 22262779HCID 22262779、化合物

生成物 1

HCID 692608743-Anilinoprop-2-enenitrile収率 170.8%

試薬・触媒・溶媒 2

HCID 7237O-Xylene溶媒HCID 8058Hexane溶媒

反応条件

温度
100 °C

実験手順

A mixture of 2-[3-(2-morpholin-4-ylethoxy)phenyl]acetonitrile (5.0 g) and N,N-diphenylformamidine (5.0 g, 25.5 mmol) in xylene (150 ml). was heated at 100° C. under a nitrogen atmosphere. After 3 h, the reaction mixture was cooled to room temperature and diluted with hexane to give 2-|3-(2-morpholin-4-ylethoxy)benzoyl[-3-phenylaminoacrylonitrile (5.0 g) as a solid.

後処理

  1. temperaturethe reaction mixture was cooled to room temperature

出典と根拠

ORDレコード
ord-f35e03778abb41cfbf59df688434c658
出典データセット
uspto-grants-2002_09
特許番号
US06444696B1

反応ノート

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