HCID 69543823, compound → HCID 59886946, compound

Participants

Reaction Steps

(step 25,26) According to procedure (Scheme 4, step 16) was prepared from (2S,4R)-4-(4-Methoxy-benzylsulfanyl)-1-(naphthalene-2-sulfonyl)-pyrrolidine-2-carboxylic acid N-methyl-N′-(4-methyl-benzenesulfonyl)-hydrazide and benzyl bromide (2S,4R)-4-(4-Methoxy-benzylsulfanyl)-1-(naphthalene-2-sulfonyl)-pyrrolidine-2-carboxylic acid N-methyl-N′-benzyl-N′-(4-methyl-benzenesulfonyl)-hydrazide which was directly deprotected according to Scheme 2 (step 4) to give (2S,4R)-4-Mercapto-1-(naphthalene-2-sulfonyl)-pyrrolidine-2-carboxylic acid N-methyl-N′-benzyl-N′-(4-methyl-benzenesulfonyl)-hydrazide as white solid, mp 82.5° C., MS: 610 (MH+).

Provenance & Evidence