HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuryl chloride → 4-(Tetrahydropyran-4-yloxymethyl)-benzenesulfonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuryl chloride | HCID 24648 | — |
| Reactant | 4-[(4-Bromophenyl)methoxy]tetrahydro-2H-pyran | HCID 22665681 | — |
| Reactant | 4-(Oxan-4-yloxy)benzene-1-sulfonyl chloride | HCID 22665753 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Product | 4-(Tetrahydropyran-4-yloxymethyl)-benzenesulfonyl chloride | HCID 22665672 | — |
Reaction Steps
This compound was prepared from 0.68 g of 4-(4-bromo-benzyloxy)-tetrahydropyran, 2 mL of n-butyllithium (1.6 N in hexane) and 0.81 mL of sulfuryl chloride using the procedure described for 58b. Yield: 0.70 g (oil), 1H-NMR (D6-DMSO): δ=1.41 (m, 2H), 1.86 (m, 2H), 3.32 (m, 2H), 3.54 (m, 1H), 3.79 (m, 2H), 4.53 (s, 2H), 7.30 (d, 2H), 7.61 (d, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06444672B1 |
| Source dataset | uspto-grants-2002_09 |
| ORD ID | ord-c98100a00de6455ebc3dd1e1cef83cbe |
| Source note | uspto-grants-2002_09 |