HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Toluenesulfonic acid → Norletimol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | Salicylaldehyde | HCID 6998 | — |
| Reactant | Benzylamine | HCID 7504 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | Norletimol | HCID 71643 | — |
Reaction Steps
A mixture of 5.0 mL of 2-hydroxy-benzaldehyde, 6.3 mL of benzylamine and 0.05 g of p-toluenesulphonic acid was refluxed in toluene for 2 hours using a Dean-Stark trap to remove liberated water. The volatiles were removed in vacuo yielding 10.1 g of crude 2-(benzylimino-methyl)-phenol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06444672B1 |
| Source dataset | uspto-grants-2002_09 |
| ORD ID | ord-696de05f6c3a4ea4b5110db9d813a8de |
| Source note | uspto-grants-2002_09 |