Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,2-Dibromoethane → HCID 838311, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,2-Dibromoethane | HCID 7839 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 6-methyl-2,3,4,9-tetrahydro-1H-carbazol-1-one | HCID 607984 | — |
| 촉매 | Tetrabutylammonium hydrogen sulfate | HCID 94433 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | HCID 838311 | HCID 838311 | — |
반응 단계
199 g. (1 mole) of 6-methyl-1,2,3,4-tetrahydrocarbazol-1-one and 376 g. (2 moles) of 1,2-dibromoethane are dissolved in 1000 ml. of toluene and stirred together with 1000 ml. of sodium hydroxide solution and 4.25 g. (12.5 m moles) of tetrabutylammoniumhydrogensulfate for 10 hours at 60° C. After evaporating the aqueous layer, distilling off the solvent and recrystallizing the residual crude product, 275 g. of 6-methyl-9-(2-bromoethyl)-1,2,3,4-tetrahydrocarbazol-1-one (90% of the theoretical) melting at 102° to 103° C. are obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04258043 |
| 출처 데이터셋 | uspto-grants-1981_03 |
| ORD ID | ord-ecbf2eb67661416ba6e34369eb482678 |
| 출처 메모 | uspto-grants-1981_03 |