Acetone → HCID 86737613, compound

Participants

Reaction Steps

0.05 Mole of 6-ethyl-9-fluoro-5,6-dihydro-3-nitro-2,5-dioxo-2H-pyrano[3,2-c]quinoline-4-ol from Example 19 (16 g) are suspended in 250 ml of water. 15 ml of acetone are added and then such a quantity of 1 N-sodium hydrogenocarbonate solution is added that the pH-value of the solution is 7.0 to 7.5. After completion of the salt formation, the whole is heated to 70° to 80° C., filtered and the crystals that have formed upon cooling are filtered off with suction. They are washed with water and dried. 14.6 g (85% of the theory) of crystals are so obtained; melting point (after recrystallization from water): 274° to 276° C.

Provenance & Evidence