HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → 7-Chloro-4-methyl-8-nitroisoquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Potassium Nitrate | HCID 24434 | — |
| Reactant | 7-Chloro-4-methylisoquinoline | HCID 20523223 | — |
| Product | 7-Chloro-4-methyl-8-nitroisoquinoline | HCID 20523218 | — |
Reaction Steps
A mixture of 17.7 g. (0.1 mole) of 7-chloro-4-methylisoquinoline and 100 ml. of concentrated sulfuric acid is treated with 10 g. (0.1 mole) of potassium nitrate dissolved in 150 ml. of concentrated sulfuric acid. The mixture is stirred for one hour, quenched on ice, made alkaline with ammonium hydroxide and filtered to yield 7-chloro-4-methyl-8-nitroisoquinoline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04258049 |
| Source dataset | uspto-grants-1981_03 |
| ORD ID | ord-a885dba6cb6a4d0f9161773f58b06d57 |
| Source note | uspto-grants-1981_03 |