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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1279323Generated: November 2, 2026

HCID 44211033, compound → HCID 44211034, compound

https://huagongshe.com/reaction/1279323

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 44211033HCID 44211033—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 44211034HCID 4421103484.4%

Reaction Steps

To a solution of (1RS, 2SR, 3SR)-3-[2-[(E)-2-carboxy-ethen-1-yl]-4-methoxyphenyl]-1- (3,4-methylenedioxy-phenyl)-5-(prop- 1 -yloxy)indane-2-carboxylic acid (43 mg, 0.08 mmol) in ethanol (5 mL) was added 10% palladium on activated carbon (40 mg). The resulting suspension was stirred overnight under an atmosphere of hydrogen then filtered through a pad of celite. The filtrate was concentrated under reduced pressure to afford the title compound (35 mg, 82%) as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06448260B2
Source datasetuspto-grants-2002_09
ORD IDord-bd3627c042a14ad9801546935fe6e4c7
Source noteuspto-grants-2002_09