Ammonium Chloride → HCID 178439140, compound

HRID 1279516Notes

Reaction equation

HRID 1279516 reaction equation
CO[C:3]1[CH:4]([CH2:10][CH:11]=[CH2:12])[CH2:5][CH2:6][CH2:7][CH2:8][N:9]=1.[Cl-:13].[NH4+:14]>CO>[ClH:13].[CH2:10]([CH:4]1[CH2:5][CH2:6][CH2:7][CH2:8][NH:9][C:3]1=[NH:14])[CH:11]=[CH2:12]

Participants

4

Reactant 2

HCID 25517Ammonium ChlorideHCID 10607182HCID 10607182, compound

Product 1

HCID 178439140HCID 178439140, compoundYield 78.3%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The product of EXAMPLE 105 (90 mg, 0.54 mmol) in 10 mL of MeOH was reacted with ammonium chloride (24.5 mg, 0.46 mmol) by the method of EXAMPLE 27 to yield 68 mg (67%) of the title material.

Sources & evidence

ORD record
ord-3aa243e59c09461d8b8958cce5b56a1c
Source dataset
uspto-grants-2002_09
Patent number
US06448286B1

Reaction notes

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