HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl chloroformate → Methyl (1,1-dimethylethyl)-(3,3,3-trichloro-2-hydroxypropyl)carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl chloroformate | HCID 6586 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 3-(Tert-butylamino)-1,1,1-trichloropropan-2-ol | HCID 23471020 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Methyl (1,1-dimethylethyl)-(3,3,3-trichloro-2-hydroxypropyl)carbamate | HCID 54278558 | — |
Reaction Steps
3-(1,1-Dimethylethylamino)-1,1,1-trichloro-2-propanol can then be reacted with methyl chloroformate at about -70° to +70° C. in the presence of an acid acceptor such as triethylamine in a solvent such as dichloromethane to produce methyl (1,1-dimethylethyl)-(3,3,3-trichloro-2-hydroxypropyl)carbamate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04258060 |
| Source dataset | uspto-grants-1981_03 |
| ORD ID | ord-c99431fe7dd146f09776d50e1cf471e1 |
| Source note | uspto-grants-1981_03 |