HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Hydroxide → rac-(3aR,7aR)-octahydro-1H-isoindol-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | (-)-trans-1,2-Cyclohexanedicarboxylic Anhydride | HCID 12261141 | — |
| Product | rac-(3aR,7aR)-octahydro-1H-isoindol-1-one | HCID 13039544 | 80% |
Reaction Steps
A solution of trans-1,2-cyclohexanedicarboxylic anhydride (10 g, 65 mmol) in ammonium hydroxide (conc., 30 mL) was hydrogenated by the method of EXAMPLE 168 to yield 7.4 g (80%) of the title material.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06448286B1 |
| Source dataset | uspto-grants-2002_09 |
| ORD ID | ord-68ca077c41184fc58447580054d574c9 |
| Source note | uspto-grants-2002_09 |