HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxonium, trimethyl-, tetrafluoroborate(1-) (1:1) → (trans)-3a,4,5,6,7,7a-Hexahydro-3-methoxy-1h-isoindole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxonium, trimethyl-, tetrafluoroborate(1-) (1:1) | HCID 2735153 | — |
| Reactant | rac-(3aR,7aR)-octahydro-1H-isoindol-1-one | HCID 13039544 | — |
| Product | (trans)-3a,4,5,6,7,7a-Hexahydro-3-methoxy-1h-isoindole | HCID 70148411 | — |
Reaction Steps
A sample of the title compound of EXAMPLE 171 (1.39 g, 10 mmol) was reacted with trimethyloxonium tetrafluoroborate (1.78 g, 12 mmol) by the method of EXAMPLE 26 to yield, after chromatography, 1.05 g (69%) of the title material.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06448286B1 |
| Source dataset | uspto-grants-2002_09 |
| ORD ID | ord-41d43ff1ed1d4c92889076b6f8f4c579 |
| Source note | uspto-grants-2002_09 |